The Department of Genetic Medicine at Weill Cornell leads a dynamic and innovative translational research program, advancing diverse fields such as Genetic Therapy and Personalized Medicine.
Our translational research program aims to leverage our expertise in genetic therapies and personalized medicine to develop clinical solutions that target the molecular causes of human diseases.
The Department of Genetic Medicine advances treatments and diagnostics through diverse clinical trials, including drug testing and research to better understand diseases.
The Department of Genetic Medicine at Weill Cornell leads a dynamic and innovative translational research program, advancing diverse fields such as Genetic Therapy and Personalized Medicine.
Our translational research program aims to leverage our expertise in genetic therapies and personalized medicine to develop clinical solutions that target the molecular causes of human diseases.
The Department of Genetic Medicine advances treatments and diagnostics through diverse clinical trials, including drug testing and research to better understand diseases.
Fiber tracking in the cervical spine and inferior brain regions with reversed gradient diffusion tensor imaging.
Publication Type
Academic Article
Authors
Voss H, Watts R, Uluğ A, Ballon D
Journal
Magn Reson Imaging
Volume
24
Issue
3
Pagination
231-9
Date Published
01/27/2006
ISSN
0730-725X
Keywords
Diffusion Magnetic Resonance Imaging, Nerve Fibers, Myelinated, Spinal Cord
Abstract
Diffusion tensor echo planar magnetic resonance imaging of the inferior brain regions and the spinal cord suffers from tissue-air and tissue-bone interfaces, which cause severe susceptibility-induced artifacts. These artifacts consist of image distortions in the phase encode direction and also affect signal intensity. To correct for these distortions, we used the reversed gradient method. We find that most in-plane voxel displacements in the inferior brain regions and the cervical spine can be corrected, yielding a good match of white matter fiber tracts with anatomical reference images. Furthermore, uninterrupted white matter fiber tracts going from the cervical spine up to cortical areas, derived from data acquired in a single acquisition, are presented.