The Department of Genetic Medicine at Weill Cornell leads a dynamic and innovative translational research program, advancing diverse fields such as Genetic Therapy and Personalized Medicine.
Our translational research program aims to leverage our expertise in genetic therapies and personalized medicine to develop clinical solutions that target the molecular causes of human diseases.
The Department of Genetic Medicine advances treatments and diagnostics through diverse clinical trials, including drug testing and research to better understand diseases.
The Department of Genetic Medicine at Weill Cornell leads a dynamic and innovative translational research program, advancing diverse fields such as Genetic Therapy and Personalized Medicine.
Our translational research program aims to leverage our expertise in genetic therapies and personalized medicine to develop clinical solutions that target the molecular causes of human diseases.
The Department of Genetic Medicine advances treatments and diagnostics through diverse clinical trials, including drug testing and research to better understand diseases.
Arterial anatomy of the talus: a cadaver and gadolinium-enhanced MRI study.
Publication Type
Academic Article
Authors
Prasarn M, Miller A, Dyke J, Helfet D, Lorich D
Journal
Foot Ankle Int
Volume
31
Issue
11
Pagination
987-93
Date Published
11/01/2010
ISSN
1071-1007
Keywords
Arteries, Talus
Abstract
BACKGROUND: Avascular necrosis following a fracture of the talar neck may be secondary to the injury itself, or may result from the surgical approach and exposure during treatment. We sought to define the arterial anatomy of the talus using gadolinium-enhanced magnetic resonance imaging (MRI) and through gross dissection following latex injection of cadaver limbs. The use of gadolinium-enhanced MRI for the evaluation of the arterial supply of the talus has not been previously reported. METHODS AND MATERIALS: We utilized 12 fresh frozen cadaver limbs to study the arterial anatomy of the talus. The anterior tibial, posterior tibial, and peroneal arteries were isolated and cannulated with polyethylene catheters. Gadolinium was injected into the cannulas, and conventional MRI sequences including suppressed and unsuppressed 3D gradient echo sequences obtained. Following MRI, latex was injected into the cannulas and gross dissection performed. In addition, the vascular constraints to anteromedial and anterolateral approaches to the talus were defined. RESULTS: MRI proved useful in the present study to confirm the presence of specific arterial branches in situ, as well as to demonstrate the rich anastomotic network in and around the talus. A branch to the medial talar neck that has not been previously identified is described which was found in nine of the specimens. This newly described branch to the medial talar neck was consistently noted to be lacerated following a standard anteromedial approach to the talus. CONCLUSION: The use of gadolinium-enhanced MRI provided very detailed images demonstrating a rich and complex anastomotic arterial network that surrounds and perforates the talus. CLINICAL RELEVANCE: A thorough understanding of the anatomy and meticulous dissection are essential to prevent unnecessary further injury to the vasculature when treating fractures of the talus.