Prevalence of diverticulosis in recurrent Clostridium difficile infection.
| Publication Type | Academic Article |
| Authors | Lipp M, Pagovich O, Rabin D, Min A, Bernstein B |
| Journal | World J Gastroenterol |
| Volume | 16 |
| Issue | 3 |
| Pagination | 345-7 |
| Date Published | 01/21/2010 |
| ISSN | 2219-2840 |
| Keywords | Clostridioides difficile, Diverticulosis, Colonic, Enterocolitis, Pseudomembranous |
| Abstract | AIM: To re-evaluate the theory that colonic diverticulosis is associated with relapse of Clostridium difficile associated disease (CDAD) in light of data suggesting increasing rates of CDAD infection and relapse. METHODS: Charts were reviewed for patients with recurrent CDAD who had also had a prior colonoscopy or flexible sigmoidoscopy. An age and gender matched control group was used to compare the prevalence of diverticulosis. RESULTS: Twenty-two patients met the study criteria, and the prevalence of diverticulosis in patients with CDAD relapse was 23% compared to 32% in age and sex matched controls (P = 0.44). A significant proportion of patients with CDAD relapse had co-morbidities associated with immune suppression. CONCLUSION: Diverticulosis does not appear to be associated with CDAD relapse. |
| DOI | 10.3748/wjg.v16.i3.345 |
| PubMed ID | 20082480 |
| PubMed Central ID | PMC2807955 |