Alphavirus entry: NRAMP leads the way.
Publication Type | Comment |
Authors | Stiles K, Kielian M |
Journal | Cell Host Microbe |
Volume | 10 |
Issue | 2 |
Pagination | 92-3 |
Date Published | 08/18/2011 |
ISSN | 1934-6069 |
Abstract | The identity of the receptors that mediate alphavirus entry into host cells has been elusive. In this issue of Cell Host & Microbe, Rose et al. (2011) use a Drosophila RNAi screen to identify NRAMP, an iron transporter with 12 transmembrane domains, as a receptor for Sindbis virus in both insect and mammalian cells. |
DOI | 10.1016/j.chom.2011.07.008 |
PubMed ID | 21843864 |
PubMed Central ID | PMC3164510 |