Publication Type Review
Authors Pagovich O, Crystal R
Journal Hum Gene Ther
Volume 34
Issue 19-20
Pagination 986-1002
Date Published 10/01/2023
ISSN 1557-7422
Keywords Immunoglobulin E, Eosinophils
Abstract Immunoglobulin E, complement, and eosinophils play an important role in host defense, but dysfunction of each of these components can lead to a variety of human disorders. In this review, we summarize how investigators have adapted gene therapy and antisense technology to modulate immunoglobulin E, complement, and/or eosinophil levels to treat these disorders.
DOI 10.1089/hum.2023.039
PubMed ID 37672523
PubMed Central ID PMC10616964
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