Peri-operative considerations in the patient with primary immune deficiency: a review.

Publication Type Review
Authors Pagovich O, Lebastchi A, Romberg N
Journal Surg Infect (Larchmt)
Volume 15
Issue 6
Pagination 672-8
Date Published 12/01/2014
ISSN 1557-8674
Keywords Communicable Disease Control, Immunologic Deficiency Syndromes, Infection Control, Postoperative Care, Preoperative Care, Surgical Procedures, Operative
Abstract BACKGROUND: Patients with inherited immune deficiency diseases often require surgical procedures, and their immune defects may predispose them to surgical complications. METHODS: A thorough review of pertinent literature and current practice guidelines on surgery in patients with immune deficiency. RESULTS: Peri-operative infections are a key, but not a singular, consideration in managing patients with a primary immune deficiency. Bleeding diathesis, gastrointestinal complications, pulmonary complications, and poor incision healing may also be idiosyncratic features unique to particular immune deficiency diseases. Patients with complex genetic syndromes that include immune deficiency also may display non-immunologic abnormalities that are equally important to surgical care. CONCLUSION: Greater awareness of primary immune deficiencies and a comprehensive evaluation of such patients in close consultation with an immunologist can minimize surgical complications and optimize patient outcomes.
DOI 10.1089/sur.2013.196
PubMed ID 25317569
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