Prevalence of diverticulosis in recurrent Clostridium difficile infection.
Publication Type | Academic Article |
Authors | Lipp M, Pagovich O, Rabin D, Min A, Bernstein B |
Journal | World J Gastroenterol |
Volume | 16 |
Issue | 3 |
Pagination | 345-7 |
Date Published | 01/21/2010 |
ISSN | 2219-2840 |
Keywords | Clostridioides difficile, Diverticulosis, Colonic, Enterocolitis, Pseudomembranous |
Abstract | AIM: To re-evaluate the theory that colonic diverticulosis is associated with relapse of Clostridium difficile associated disease (CDAD) in light of data suggesting increasing rates of CDAD infection and relapse. METHODS: Charts were reviewed for patients with recurrent CDAD who had also had a prior colonoscopy or flexible sigmoidoscopy. An age and gender matched control group was used to compare the prevalence of diverticulosis. RESULTS: Twenty-two patients met the study criteria, and the prevalence of diverticulosis in patients with CDAD relapse was 23% compared to 32% in age and sex matched controls (P = 0.44). A significant proportion of patients with CDAD relapse had co-morbidities associated with immune suppression. CONCLUSION: Diverticulosis does not appear to be associated with CDAD relapse. |
DOI | 10.3748/wjg.v16.i3.345 |
PubMed ID | 20082480 |
PubMed Central ID | PMC2807955 |