Secondary structures for splice junctions in eukaryotic and viral messenger RNA precursors.

Publication Type Academic Article
Authors Trapnell B, Tolstoshev P, Crystal R
Journal Nucleic Acids Res
Volume 8
Issue 16
Pagination 3659-72
Date Published 08/25/1980
ISSN 0305-1048
Keywords Genes, Viral, RNA, Messenger, RNA, Viral
Abstract Thermodynamically stable secondary structures have been found for adjacent splice junctions of 17 introns from 10 eukaryotic and viral mRNA precursors. Complementary regions in these structures position the exons to be ligated in a favourable orientation for splicing. The possible role of these structures in a general splicing mechanism in described.
DOI 10.1093/nar/8.16.3659
PubMed ID 6253906
PubMed Central ID PMC324182
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